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Purkinje fibers initiate spontaneous action potentials, which cause the ventricles to contract early.
Action potentials are not delayed sufficiently at the AV node.
Spontaneous action potentials in the SA node overlap such that the repolarizing phase of one action potential cancels out the depolarizing phase of the next.
Action potentials propagate into the ventricles before the contractile cells have repolarized from the previous heartbeat.
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Ask by Estrada Long. in the United States
Jan 22,2025

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Purkinje fibers can initiate action potentials, causing early ventricular contractions. The AV node delays electrical impulses to ensure proper atrial and ventricular coordination. Overlapping action potentials in the SA node can lead to irregular heartbeats. Action potentials in the ventricles can occur before the previous heartbeat has fully repolarized, potentially causing arrhythmias.

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The Deep Dive

The Purkinje fibers are fascinating components of the heart’s conduction system. They allow for a rapid and coordinated contraction of the ventricles, ensuring that the heart pumps blood efficiently. This unique fiber network plays a pivotal role in the heart’s electrical system, helping to prevent chaotic rhythms that can occur if the timing of contractions is disrupted.
In practice, understanding the timing of action potentials is crucial for diagnosing and treating cardiac arrhythmias. Medications can be designed to target specific phases of these action potentials, and interventions like catheter ablation can help correct conduction pathways that may lead to dangerous scenarios like fibrillation, ensuring the heart works as a well-tuned machine!

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