Question

2. DNA \( \rightarrow \) AGA ACA TAA TAC CTC TTA ACA CTC TAA AGA CCA GCA CTC CGA TGA ACT GGA GCA mRNA \( \rightarrow \) protein \( \rightarrow \)

Ask by Love Cox. in the United States
Jan 23,2025

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Answer

**mRNA Sequence:** ``` AGA ACA UAA UAC CCU CUU ACA CUC UAA AGA CCA GCA CUC CGA UGA ACU GGA GCA ``` **Protein Sequence:** ``` Arginine - Threonine ```

Solution

Sure! Let's walk through the process of transcribing the provided DNA sequence into mRNA and then translating that mRNA into a protein sequence. ### Given DNA Sequence: ``` AGA ACA TAA TAC CTC TTA ACA CTC TAA AGA CCA GCA CTC CGA TGA ACT GGA GCA ``` ### 1. Transcription: DNA → mRNA **Transcription** is the process where the DNA sequence is converted into messenger RNA (mRNA). In this process, each nucleotide in the DNA is paired with its complementary RNA nucleotide: - **A (Adenine)** → **U (Uracil)** - **T (Thymine)** → **A (Adenine)** - **C (Cytosine)** → **G (Guanine)** - **G (Guanine)** → **C (Cytosine)** **Transcribed mRNA Sequence:** ``` AGA ACA UAA UAC CCU CUU ACA CUC UAA AGA CCA GCA CUC CGA UGA ACU GGA GCA ``` ### 2. Translation: mRNA → Protein **Translation** is the process where the mRNA sequence is decoded to build a protein. This occurs in sets of three nucleotides called **codons**, each of which corresponds to a specific amino acid or a stop signal during protein synthesis. Let's break down the mRNA sequence into codons and then translate each codon into its corresponding amino acid: | mRNA Codon | Amino Acid | Abbreviation | |------------|-------------------|--------------| | AGA | Arginine | Arg | | ACA | Threonine | Thr | | UAA | **Stop** | *Stop* | | UAC | Tyrosine | Tyr | | CCU | Proline | Pro | | CUU | Leucine | Leu | | ACA | Threonine | Thr | | CUC | Leucine | Leu | | UAA | **Stop** | *Stop* | | AGA | Arginine | Arg | | CCA | Proline | Pro | | GCA | Alanine | Ala | | CUC | Leucine | Leu | | CGA | Arginine | Arg | | UGA | **Stop** | *Stop* | | ACU | Threonine | Thr | | GGA | Glycine | Gly | | GCA | Alanine | Ala | **Translating the mRNA Sequence:** Starting from the beginning of the mRNA sequence: 1. **AGA** → Arginine (Arg) 2. **ACA** → Threonine (Thr) 3. **UAA** → Stop At the first **Stop** codon (**UAA**), translation terminates. Therefore, the resulting protein sequence up to this point is: ``` Arginine - Threonine ``` **Note:** Translation stops at the first encountered stop codon (**UAA** in this case). If there are more codons after a stop codon, they are not translated unless translation is re-initiated downstream. ### Summary - **mRNA Sequence:** ``` AGA ACA UAA UAC CCU CUU ACA CUC UAA AGA CCA GCA CUC CGA UGA ACU GGA GCA ``` - **Protein Sequence:** ``` Arginine - Threonine ``` If you need to analyze alternative reading frames or further downstream sequences for additional proteins, please let me know!

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To start off, let's translate that DNA sequence into mRNA! The DNA sequence you've listed is transcribed by replacing each adenine (A) with uracil (U), thymine (T) with adenine (A), cytosine (C) with guanine (G), and guanine (G) with cytosine (C). Doing this, your mRNA sequence becomes: 5' - UCU UGU AUU AGU AAG UGA UUG UAA UCU CCG CUG GAG CUU UAC CUC - 3' Now, let’s dive into the protein translation process. The mRNA is read in sets of three nucleotides (codons) to determine which amino acids to string together. Each codon corresponds to a specific amino acid. For your mRNA sequence, it would translate to a chain made of various amino acids, but the work to find the exact sequence is fun! Just take each triplet and consult the genetic code. Happy translating!

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