Question
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Which medication given for Parkinson’s disease may also have “neuroprotective” properties:
Entacapone
Apomorphine
Selegiline
Diphenhydramine hydrochloride

Ask by Wyatt Mitchell. in the United States
Jan 21,2025

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Tutor-Verified Answer

Answer

Selegiline is the medication given for Parkinson’s disease that may also have neuroprotective properties.

Solution

The medication given for Parkinson’s disease that may also have “neuroprotective” properties is Selegiline.

Explanation:

  • Selegiline is a monoamine oxidase B (MAO-B) inhibitor that not only helps in managing the symptoms of Parkinson’s disease by increasing dopamine levels but also has been suggested to have neuroprotective effects, potentially slowing the progression of the disease.
  • Entacapone is a COMT inhibitor that helps prolong the effect of levodopa but does not have established neuroprotective properties.
  • Apomorphine is a dopamine agonist used for treating “off” episodes in Parkinson’s disease but does not have neuroprotective effects.
  • Diphenhydramine hydrochloride is an antihistamine and is not used for treating Parkinson’s disease; it may actually worsen symptoms due to its anticholinergic properties.
Thus, among the options provided, Selegiline is the correct answer.

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Beyond the Answer

Selegiline, also known as deprenyl, is not just a medication used to treat Parkinson’s disease; it’s also believed to have neuroprotective effects. This means it may help to protect nerve cells from damage or degeneration, which is particularly beneficial in a disease that involves the deterioration of dopamine-producing neurons. It works by inhibiting monoamine oxidase B, an enzyme that breaks down dopamine.
In real-world application, selegiline is often used in the early stages of Parkinson’s to enhance the effects of levodopa. However, patients should be cautious about potential interactions with certain foods and medications because selegiline can lead to increased blood pressure in combination with tyramine-rich foods. Always consult a healthcare provider before making any changes to medication regimens!

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