Which clinical manifestations is the patient likely to show when he or she has reached stage 2 of the Unified Parkinson's Disease Rating Scale (UPDRS)? Akinesia, rigidity, and severe disability Early postural changes, social withdrawal, and depression Substantial gait disturbances and moderate generalized disability Slight tremors or minor changes in speech, facial expression, posture, or movement

At stage 2 of the Unified Parkinson's Disease Rating Scale (UPDRS), patients typically exhibit slight tremors or minor changes in speech, facial expression, posture, or movement. These early signs can impact daily activities, but they are often subtle enough that the patient may still manage most tasks independently. Additionally, this stage may see a few early postural changes and, in some cases, slight social withdrawal as individuals begin to notice changes in their physical abilities. However, they usually maintain a level of independence, which can make it tricky to identify the progression of the disease at this point.