Which is the most serious neurologic adverse effect the nurse should monitor for in a patient taking amantadine hydrochloride? Confusion Disorientation Seizure disorder Mental depression

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The most serious neurologic adverse effect to monitor for in a patient taking **amantadine hydrochloride** is the development of a **seizure disorder**.

**Rationale:**

- **Amantadine** is primarily used to treat Parkinson's disease and as an antiviral for influenza A. While it offers therapeutic benefits, it can also lead to several central nervous system (CNS) side effects.
  
- **Seizure Disorder:** Seizures are considered a severe adverse effect because they can pose immediate risks to the patient's safety, including injury during a seizure event. Seizures can also indicate significant CNS irritation or excitotoxicity caused by the medication.

- **Confusion and Disorientation:** These are important symptoms to monitor as they can affect the patient's ability to function and adhere to treatment. However, they are generally less acutely dangerous than seizures.

- **Mental Depression:** While depression is a serious condition that requires attention, it typically doesn't pose the immediate physical risks associated with seizures.

**Therefore, nurses should prioritize monitoring for seizures when patients are on amantadine hydrochloride.**

**Answer:**  
Seizure disorder is the most serious neurologic adverse effect to monitor.
Seizure disorder is the most serious neurologic adverse effect to monitor for in a patient taking amantadine hydrochloride.

Which is the most serious neurologic adverse effect the nurse should monitor for in a patient taking amantadine hydrochloride? Confusion Disorientation Seizure disorder Mental depression

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