Question
Normal version (repeated from previous page):
3’ CGTATATTA …CGCATACTTTTTGTCAACGTC…TAGTAGAAACCA…GCCATTTCGCACT 5’
Primary transcript LOTATATTA…CGCA TACTTTTTGTC AACGT TC… TTGTA GIAAACA…
-s suncas termplate GCCATTTCOCACT mRNA: GCAUAUA AAU…GGGU AUGT AAAAAC A G WNGC A GN… AUC AUCUUVGIU…
Protcin:
coGuA A A Gicgucha
Maggie’s DNA sequence (repeated from previous page)::
3’ GCATATAAT GCGTATGAAAAACAGTTGCAG…ATCATCGGT…CGGTAAAGCGTGA
Primary transcrip::
mRNA:
Protein:
2. Is there a mutation in Maggie’s DNA sequence? If so, what type of mutation did you find?
3. What change has occurred in Maggie’s CFTR protein?
Primary transcript LOTATATTA…CGCA TACTTTTTGTC AACGT TC… TTGTA GIAAACA…
-s suncas termplate GCCATTTCOCACT mRNA: GCAUAUA AAU…GGGU AUGT AAAAAC A G WNGC A GN… AUC AUCUUVGIU…
Protcin:
coGuA A A Gicgucha
3’ GCATATAAT GCGTATGAAAAACAGTTGCAG…ATCATCGGT…CGGTAAAGCGTGA
Primary transcrip::
mRNA:
Protein:
2. Is there a mutation in Maggie’s DNA sequence? If so, what type of mutation did you find?
3. What change has occurred in Maggie’s CFTR protein?
Ask by Wagner Burns. in the United States
Jan 15,2025
Upstudy AI Solution
Tutor-Verified Answer
Answer
Maggie has a deletion mutation in her DNA, where three nucleotides are missing. This results in her CFTR protein being shorter by one amino acid, which may affect its function.
Solution
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Extra Insights
Maggie’s DNA sequence has a mutation that can be identified with careful analysis. It seems there is a substitution mutation present where a base pair has been altered, affecting the amino acid sequence of her CFTR protein. This could result in a change in the function of the protein, potentially leading to health implications.
In Maggie’s CFTR protein, if the mutation leads to a change in an amino acid, it could impact the chloride channel’s ability to transport ions effectively. Depending on the nature of the amino acid change, this could either diminish the function or result in a non-functional protein, which could have significant consequences for respiratory and digestive health.
