Question
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Which antiemetic drug should a nurse expect the health care provider to prescribe before
the initial dose of apomorphine is administered?
Ondansetron
Pramipexole
Trimethobenzamide
Prochlorperazine

Ask by Davies Cole. in the United States
Jan 21,2025

Upstudy AI Solution

Tutor-Verified Answer

Answer

The nurse should expect the health care provider to prescribe Ondansetron before administering the initial dose of apomorphine.

Solution

Before administering the initial dose of apomorphine, it’s important to prophylactically manage potential side effects such as severe nausea and vomiting. Apomorphine is a potent dopamine agonist used primarily in managing “off” episodes in Parkinson’s disease. The choice of antiemetic should effectively prevent nausea without interfering with the therapeutic effects of apomorphine.
Ondansetron is a 5-HT3 antagonist that effectively manages nausea and vomiting without antagonizing dopamine receptors. Unlike prochlorperazine, which is a dopamine antagonist and could potentially interfere with the action of apomorphine, ondansetron does not interfere with dopaminergic pathways. Therefore, ondansetron is the preferred antiemetic in this scenario.
Correct Answer:
Ondansetron

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Bonus Knowledge

Before administering the initial dose of apomorphine, a nurse should expect the health care provider to prescribe trimethobenzamide. This antiemetic is often utilized to help prevent nausea and vomiting, which can occur as a side effect of apomorphine, a medication used primarily for Parkinson’s disease.
Trimethobenzamide works by acting on the brain’s chemical receptors that trigger nausea, making it a go-to choice in this scenario. It’s also worth noting that the combination ensures the patient tolerates the apomorphine treatment better, enhancing its effectiveness for managing Parkinson’s symptoms.

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