19. \( \left(-18 m^{2} n\right)^{2}\left(-\frac{1}{6} m n^{2}\right) \)
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To simplify the expression \( \left(-18 m^{2} n\right)^{2}\left(-\frac{1}{6} m n^{2}\right) \), we start by squaring the first term: \[ \left(-18 m^{2} n\right)^{2} = (-18)^{2} (m^{2})^{2} (n)^{2} = 324 m^{4} n^{2} \] Next, we multiply this result by the second term \(-\frac{1}{6} m n^{2}\): \[ 324 m^{4} n^{2} \cdot \left(-\frac{1}{6} m n^{2}\right) = 324 \cdot -\frac{1}{6} \cdot m^{4} \cdot m \cdot n^{2} \cdot n^{2} = -54 m^{5} n^{4} \] Thus, the simplified expression is: \[ \boxed{-54 m^{5} n^{4}} \]