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Question
01/16
Antigens are made from which macromolecule?
Lipids
Carbohydrates
Nucleic Acids

Ask by Clark Beck. in the United States
Mar 24,2025

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Carbohydrates are the macromolecules that antigens are made from.

Solución


An antigen is a substance that induces an immune response, usually by being recognized as “non-self” by the immune system.

Most antigens encountered in immunology are proteins. In fact, proteins are the most frequent type of antigen because they have complex three‐dimensional structures and multiple epitopes that the immune system can recognize.

The provided answer choices are:
  • Lipids
  • Carbohydrates
  • Nucleic Acids
Since proteins are the most common antigens but are not given as an option, we analyze the remaining macromolecules.
  • Lipids by themselves are generally not strongly immunogenic; however, they can become antigenic when attached to proteins (forming glycolipids).
  • Nucleic acids are typically not immunogenic on their own.

Carbohydrates, such as bacterial capsular polysaccharides, can serve as antigens. Although they often induce a T-cell independent response (which may be less robust than responses to protein antigens), they are recognized by the immune system as antigenic.

Out of the given options, the most correct answer is

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Extra Insights

Antigens are primarily composed of proteins, which are macromolecules made up of amino acids. These proteins can be surface markers on pathogens like bacteria and viruses, or they can be found on the surfaces of cells, triggering an immune response when recognized as foreign by the body. Think of them as the unique “name tags” that let your immune system know which cells belong and which do not!
In the real world, the concept of antigens is pivotal in vaccine development. Vaccines often contain harmless parts of the pathogen (like inactivated or weakened antigens) that stimulate the immune system to produce a response. This preparation teaches the body how to recognize and fight off actual infections without having to endure the full disease, making vaccinations a crucial public health tool!

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